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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b3221398b853deaa0f32135361be088006091cf126236b7670da0e129268a7' 
  AND token = '0WL5nMh8B38pukN2wzyiYNAjBtLCj2oTG8fjwjbKYAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}