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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3669a7ee11aabf24c6ad104cb4f95adc9c13deb3153e5af45b5124856c9c4b40' 
  AND token = 'R3VJl2FLlNnSXeZ1YkgAIfsy3Dh5iDkAyIa6su+M5L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}