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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74525a1a6a9f90f145a27668a844696927d9987789e7c3163ea74ceef272bfd3' 
  AND token = 'x3RL6CxBYAdp8lNUxiUlDQcw/yqGDp4TO5hRwlYGPTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}