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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4902d7142eb9a5e534935eb4057f0266e9e85f329c6d28bb56764c995d070f35' 
  AND token = 'YsvnyBwbiqjIpnBjcDsmRcuoU7qS0iIFZ7lmdDphw80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}