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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd282aa043e4fd8e236623560086b7557179d7e737702fa3a211f93909609e6d0' 
  AND token = 'wJaZjAeeAP5gpdPwwPTvwy+b/N2dPs8xQRAT5xzwFKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}