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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4666f73d570e6c64fc53b87aad171efc91bee4c3d0c48b50a05cf29d73aacac9' 
  AND token = 'eBoSTSg9oitAGFfNfltSq36wS7OUfnZz+TEx+IB5gSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}