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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbb4013c1e86b490144080f6f41c6c07075f71cc320a9a243e09529586fc450b' 
  AND token = 'oW374Ts/bpDhDXd1UjMtpF7WE8+gDItC2gKlSvhJTNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}