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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04df73945ef692bbaafff8993f640f911fbc389c76fc40b4009d87b3c5153bec' 
  AND token = 'FDVCyIzn53y+FQ8R0RRyEdfi6gnWc1Vxghpr0g1Fd3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}