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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4905cc96f2d09676d97c312a654c096fdbbdb4d31f3af1fff89dadea8e90202' 
  AND token = 'n6WI1wb5oElwMv83j2uCmhyr5E7Hn5WMWaCi1aNX9H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}