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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a132d245cf6a2a2da50953753537601ebb7529904fadfce479660c134d55c6' 
  AND token = 'e89Piptou5PuM/5C02ePBB81U/y+d5g7EKrtmS1aln4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}