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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8861e2d09da1135dbfac1b6d50ff0e7f9993c7bf6fd497f64a0f1ddf809fae5c' 
  AND token = 'ghQDJkXWcc4f45URdw0HNVcsJyL5TSkvzCv79F9bQgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}