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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a78078e8f8d0a7dc742e3ade673d7b585e7aba73b9b911a27bd80def091c0bc' 
  AND token = 'A5EY6fsmsnUW9cqZyy6dSpQdQRePNfxI8MArfo1L71w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}