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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65c72ff2e359e8d37545a8d270f68469054a21eaafec0fe8d145ff570b00e14' 
  AND token = 'k+6u5ZXgjnp9wWRstYxDEeCgE8NURtFLtBNM2svmhrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}