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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '396b5443f0f681b0111cfcccc81cbbfa44e0695dd73e64652d7fc19f1f265e11' 
  AND token = 'LH0t5XLBr/LUDUCkasbkI3Ys78qFouIpZauHxGF5fg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}