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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bed58bb4d1c31ced47cc94013c83fcc062dd5e7de5517231c49a15b07991f7b' 
  AND token = 'CBwwLslqMkOODglh6LJYWyN4tQZdJ5RknkMq/2uCE7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}