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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75247b1eef1dffaa8e3f95f62d95e80ffe3c681f987e827dd4855b6b323dfd8' 
  AND token = 'CMofRLIDvNnfJEZtA9AQPd7WP+uAZctKGNbU0rgR+fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}