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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f23ee053e17e54e39a6e7a4567ea115e8e5cf554ad12ea8aa53b8e89c919ca64' 
  AND token = 'r8eSJHqOO1Wdf2Pe4XXyE30I+HfnWmb1SBCvESfXjuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}