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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4627cce17f0da5a19f32490bba4cb3d35e7b6cca0d6192c5a54005dadcbb29aa' 
  AND token = '+fC0AeShTogHg85Pb8+CTZHtXmfNyKs0wdtOd+gQ2mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}