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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef28621a520fa8d20186e75c689b1a2482a9180d58a5cacc0c65bff85b691abe' 
  AND token = 'WKdXxMrAkarO2Xb6Ka3UBDJqoP1Ylm5afQk51EAm800=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}