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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8380067b55b6fe56b5dfeb98488c9b1a57169cc3dda8b8620a8ed52fc40c1da4' 
  AND token = 'CKxrwPH6xDBqLZblTlF5MXxpRncjBlSIR4UD/N76e18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}