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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d05e5c0fd5f6db3642ab8e5337c3fd58cdb9e95e1221244de15e0601491127' 
  AND token = 'U6Ri/YLI80yAHNoNO9EZg8ttOXBgP3nJWVnlTdd3UIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}