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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380595981def19b03e84b5ce817127be3fa551b175df1a42c660f67405dc41ed' 
  AND token = 'rP07S/OXcxycnHu5fPp+Fi1HqpCygtOSBo6Oqx1BMzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}