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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b95d58662b5f18e189c1a0890a89ade826ccd4b063ddbeade95671a9a1b293a6' 
  AND token = 'xyimfXs+tIn3tEiany1Gos+0shMDK0dBZyFPRynAvZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}