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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6554dce68eca3d63d5bec60ce2ca85ae5f802a0827e890df9eb044973ac7fe6c' 
  AND token = 'hRFaOZNSfD9dyfMKviVVoeGDOpWKCqz0pz//qaGQ1PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}