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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af69b91d116da577fe531ac09f70e5f3bcaafe7aab1ef297ff4f2bae2ae151f5' 
  AND token = '+rQ44/Zg8cS+ztOdfZFKlzWMtlkAvI2Sv2m33HsAX6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}