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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022a70a7eca4f2a3b411d87785fa0eeb81b3fcf43adf732c1ad1e217256d080b' 
  AND token = 'XVfiFRksdA9g2IZa94Gm3qhvbr8m0z7TlZU7p2hhB4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}