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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8a7acf4c4158e99e8b448761c151221d63c464ab0561f25da3e8b6f7a1b5ed4' 
  AND token = 'zc+uvSZL4cEtTIXKnL0DTLlIVMGGBy8H5M7h6aHByK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}