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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e5fa9e07913955538e5fd4e13d062f07509fe226ec2124c4f4f825d027c199' 
  AND token = 'nCAo3tz6swIKtFs2Yyfny0ZK+DMk/VSs+ZXvgT0bC9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}