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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca57f6c364ada63377f4fe8b15f09b30dd30d9feb802b7050cdb5854db4e927' 
  AND token = '8InP+DKbAWhan8r2YMCa6SbMTssyD7chQe3ImYfHQcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}