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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b03718f268a74e7a46968c33cd20a65d3508f0f8fea395c3e5c3c7719cdb20' 
  AND token = 'i1tqTDJhJjCTF5ToDZ5ClRxgKktLA148EUg0nDMmO6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}