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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37be8fa6b871f8c81fe5a65797a66e5f49cf3a51d464a657782363ae9ef14391' 
  AND token = 'hmKdORL6dyxvBPs1UDPum1efwwmQr+MF8eaonFizKhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}