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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d112df30479d848d301f02380726e24b9d96f0b9b59419ae022ecd0ee2b9c2d' 
  AND token = 'pcgApHPAA8QHRGqobSh1GWu4oDbCT7P3Z2EhwbwygrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}