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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e5808dffe855ccf2f5a6e232f749e9d3497e4e1a576e57e45234618e0a1aa4' 
  AND token = 'KpMH7Qr3p9SZqDzSITTuyoUFgEg8HkXbU//15jZcllw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}