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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a48ca5fa8a6b0f9f6895eaff7f148fcca2a3469862753a29a1fc5a8868366b5' 
  AND token = 'ua0k2iIrzXlmAQ+igkdwESwjdgT1IXEt3In4OkJsUMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}