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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4bdc022a6da2e0f3656c9c5a10e1242b8f946a3b65af389a9f0f386fc6a265' 
  AND token = 'RVgIIhsLef58+M9sqF5owYAaItiJRilB7bO4YkZm7yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}