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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4aa2c35940b6ce3e08fa0ff66ad0651948701076e7cf55a24f14183bc264c33' 
  AND token = 'KacFKKOJ6qIl0OvRgD50x7WqP6l5eyXcFfMd7uzIoXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}