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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '960cca63f722a6621f4d25806e146492e1c90e3bc693d2088a74f07fdc5b7373' 
  AND token = 'uvuYolwdzrIfWMdQSX98WlwRG36d60OcL4mD6SP8LBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}