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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eceb8009f24cea9416129233a01d5d9299f6e2f1b53cbf5c30c52e8bcb982010' 
  AND token = 'obmg9LuyNFwmfKmyoSHuv4TQgrow3KkOcusnvvl4KUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}