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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f117e6675d4d56a6eea2b7cabb73644fbed250bf983a5a0b0e496210d175b3c8' 
  AND token = '3cVBB0IhjehTj1wiDIp7BXwcm9yWe+bYsLp+D2LSGEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}