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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '314951f710b1639affc610ca53553a2e225e2ce10b12fc52ad54c3c6ab3843b1' 
  AND token = 'sUsF/0GIKxQ82kKbIqnlOy/GQQ23iNokTQkMCPSnHS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}