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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ae8ce302a837e81755c3660aeb279bce8ac9d35483dadf3acc76eea6a4508d' 
  AND token = 'J6tmJjvtcJUPdSLJHUJw2H7wAIvKEd+prTniLvmh8as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}