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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ccd69ab855b1e8c261afbacc8d0b70557083d5da2bec81922e02b9a456c815' 
  AND token = 'H1zJ1exB6vMjDby7PpNmwg3OKpW8WiZ+R4VfNDdmyOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}