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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b354339d2e04b6e8c5c17dae5fd61118496965c86bac13a77019f369b5940b8c' 
  AND token = 's1PKJJPwFXWYLOWdvjqHMyCxiQ07GIypgMEB9NO1AEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}