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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427cead4e4b8cfcf9ae3937827f9c5b099c57ee265f21845c275a90d04878f6e' 
  AND token = 'bvyvkLzdcg2V4I4RzxUvMUvX4hyJQ8sUfaH5HITgC2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}