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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ecef84f348f2a4ac6e0b850379df1e1cae0654bf1abba2a30fb89588dc1624a' 
  AND token = 'gt74d+FdQTD/48Puw8c4I1bzPJvWRbnEbSo6hy52eIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}