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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641cdb69ee174aaaecdf70b46ed29d2a568281d67f273009044d021564395338' 
  AND token = '5663c46N77gL9GSNvlQXLAxJoKpimaPjnzSN1y2JH4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}