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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7e9bb3c1edc779aa7846641b5641530eb3f1893eef59e1b07b322eac29f310c' 
  AND token = 'ACLyCm7GiLHDo4l/hdMHCMt3edoe/E6ur5CG+gvF84M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}