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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3176a8b66a0aece8868824df9b816beb46c44c216d8cd3b8ec70980ce3db785d' 
  AND token = 'DISTqXhIyjaoDV93OV4gpc0+8zUf7sQnN7TGLAtlDRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}