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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916641cd573b52a92007a21525e1c0535a7cd3ecaf1480eb6d11fd9817eb8983' 
  AND token = 'YEdaA+7ia3ZRj5lvbWfEiasBCjfih4G1oSKAoLgkc+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}