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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49de605998cfb287b8c0ca4c1d6d9477d2d0888d3bd276a14567a4ee4b5a2f47' 
  AND token = 'HL0dDH32y07AVLGIOuXrignr4cgSsn6Dhu8TAwiIyZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}